Endocrine Abstracts

Introduction: Proton pump inhibitors (PPIs) are widely used for treating various upper gastrointestinal disorders. A well-known side effect of PPI therapy that may cause serious differential diagnostic problems is the elevation of serum chromogranin A (CgA).Objective: We report a case with highly elevated serum CgA in a patient with bilateral adrenal adenomas that was clearly associated with PPI therapy. Suspension of PPI intake for a few days resulted i...

A 17-year-old boy was referred to our Department. In his medical history Crohn’s disease had been supposed because of abdominal pain and distention. He had previously undergone minor surgery as having large tongue with neuromas and hypertrophic gums. Due to his marfanoid appearance, arachnodactyly, massive eyebrows and lips together with his medical history, multiple endocrine neoplasia type 2B (MEN2B) was suspected, which is a very uncommon hereditary disease. It consist...

A 57-year-old female patient was admitted for evaluation of multiple focal liver lesions diagnosed with abdominal ultrasound and CT. Her medical history included severe rheumatoid arthritis and pernicious anaemia treated with vitamin B12. Gastroscopic examination revealed numerous small polypoid lesions within the stomach, and histology of tissue samples obtained by biopsy showed carcinoid associated with atrophic gastritis. Although the patient had no symptoms of carcinoid sy...